Sickle Cell Disease Insights

Hydroxyurea Effective Long-Term for Sickle Cell

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Latest Research

Recent research has focused on developing innovative detection methods for diseases like Sickle Cell Anemia. Krishnan and Kumar (2025) A notable study involves using an MXene coated concave shaped microchannel PCF SPR biosensor to enhance detection capabilities. This biosensor exploits differences in cell properties, such as refractive indices, to improve diagnostic accuracy.

The development of such biosensors is crucial for early detection and management of diseases like Sickle Cell Anemia. By leveraging advanced materials and technologies, researchers aim to create more effective diagnostic tools. This work contributes to broader efforts to address widespread diseases and could lead to significant advancements in healthcare diagnostics and treatments Krishnan and Kumar (2025).

Clinical Trials

This is a list of upcoming or ongoing clinical trials that are actively recruiting and have been listed or updated in the last two weeks:
Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease
Study Type
Phase I
Location
Maryland
Age Range
18 - 65 Years
Enrollment
25
Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease
Study Type
Phase II
Location
District of Columbia
Age Range
4 - 21 Years
Enrollment
99
A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)
Study Type
Phase III
Location
2 countries
Age Range
12 - 100 Years
Enrollment
315
Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants
Study Type
Observational
Location
Maryland
Age Range
18 - 70 Years
Enrollment
300

Community News

Global Alliance of Sickle Cell Disease OrganizationsGlobal Alliance of Sickle Cell Disease OrganizationsApr 16, 2025

5 Ways a Sickle Cell Warrior Can Live Their BEST Life

Dear Sickle Cell Warriors,

Always know You've got this! Living well with SCD is possible.

Believe in yourself and your strength.

You're a warrior, and warriors are resilient and courageous.

SCD Association of America, IncSCD Association of America, IncApr 18, 2025

Some snapshots from this past month! SCDAA President and CEO Regina Hartfield was proud to represent our organization during the Sickle Cell Foundation Inc. Conference. The theme was "Sickle Cell Disease: Call to Action, From Policy to Implementation." Thank you to SCF for hosting this important and enlightening event.

SCD Association of America, Inc Post
Sick CellsSick CellsApr 16, 2025

The momentum from this year’s SCD Policy Forum is still going strong.

Thank you to everyone who showed up, spoke out, and made your voice heard. This was our largest turnout yet, with more meetings than ever before—a true testament to the strength and unity of the sickle cell community.

But our work doesn’t stop here. We hope you continue to feel empowered to stay engaged, raise your voice, and push for the change our community deserves.

Swipe through for a look at the highlights from the SCD Policy Forum and the impact you helped make possible.

Sick Cells Post

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